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Ocean Re-New ®Lifting night cream improving periorbital wrinkle andforehead wrinkle

Hi-Q Marine Biotech International Ltd. for the evaluation of the efficacy of Ocean Re-New®

Lifting night cream in improving periorbital wrinkle and forehead wrinkle has been conducted following the guideline of Korea Ministry of Food and Drug Safety (MFDS) on clinical and efficacy testing of cosmetics and the Standard Operating Procedures (EL-P-7400) of Ellead Co., Ltd. after the approval based on standard operating procedures of Ellead IRB.


Ocean Re-New® Lifting night cream

1. Number of volunteers: 24 (final 22 females, average 58.00 ± 5.51 years old)

2. Study period: 4 weeks (measurement points: baseline, after 1 week, 2 weeks and 4

weeks of application)

3. Test site: face

4. Method of application: twice a day (morning and night), after washing the face, take

an appropriate amount (0.5 g) of the test product and apply on forehead, cheeks, nose

and chin, then massage evenly into face at the last step of skin care.

5. Evaluation details

1) Assessment of periorbital wrinkle and forehead wrinkle by Antera 3D® CS

2) Self-assessment by volunteers

3) Assessment of adverse skin reactions by volunteers and dermatologist



Research institution: Ellead Co., Ltd.

  • The first professional institution for human clinical trials of cosmetics in South Korea

  • Registered Institutional Review Board (IRB) in South Korea and the United States

  • Developed multiple patented efficacy testing technologies

  • Assisted the MFDS in South Korea in establishing various cosmetic efficacy evaluation guidelines

  • Owns a database of approximately 50,000 Asian skin test subjects

Representative director:Kyung Soo Byun President

Research director:Tae Kee Moon, M.D. Dermatologist


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